Appeal court rejects latest challenge to adding VAT to UK private school fees

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This was especially vexing to physician and bacteriologist Robert Koch, who, in seeking to culture his bacteria, “bent all his power to attain the desired result by a simple and consistently successful method,” wrote bacteriologist and historian William Bulloch in his 1938 book, The History of Bacteriology. “He attempted to obtain a good medium which was at once sterile, transparent, and solid” and got some results with gelatine.6 But gelatine is easily digested by many microbes and melts at precisely the temperatures at which the disease-causing microbes Koch wanted to study grow best.

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Massively parallel reporter assays across five cell types identify thousands of causal, noncoding regulatory variants among 220,000 loci, revealing diverse regulatory mechanisms shaping complex traits and disease.